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Isotretinoin: a drug to avoid for professional athletes?

John MillerBy John MillerOctober 24, 2025No Comments4 Mins Read
Isotretinoin: a drug to avoid for professional athletes?
Isotretinoin: a drug to avoid for professional athletes?
  • Table of Contents

    • Isotretinoin: A Drug to Avoid for Professional Athletes?
    • The Use of Isotretinoin in Professional Sports
    • The Risks and Side Effects of Isotretinoin
    • Expert Opinion
    • Conclusion
    • References

Isotretinoin: A Drug to Avoid for Professional Athletes?

Isotretinoin, also known as Accutane, is a powerful medication used to treat severe acne. It is a synthetic form of vitamin A and works by reducing the amount of oil produced by the skin’s oil glands. While it has been proven to be highly effective in treating acne, it has also gained attention in the world of sports as a potential performance-enhancing drug. However, the use of isotretinoin by professional athletes is highly controversial and has raised concerns about its potential risks and side effects. In this article, we will explore the use of isotretinoin in professional sports and why it should be avoided by athletes.

The Use of Isotretinoin in Professional Sports

Isotretinoin has been banned by the World Anti-Doping Agency (WADA) as a performance-enhancing drug since 2006. This ban was put in place due to its potential to improve athletic performance by reducing the production of sebum, which can lead to improved endurance and strength. In addition, isotretinoin has been reported to have mood-enhancing effects, which can give athletes a psychological advantage during competitions.

Despite its ban, there have been cases of professional athletes using isotretinoin to improve their performance. In 2016, Russian tennis player Maria Sharapova tested positive for the drug and was subsequently banned from competing for two years. Sharapova claimed that she had been prescribed the medication for medical reasons and was unaware of its banned status. However, this incident shed light on the potential use of isotretinoin as a performance-enhancing drug in professional sports.

The Risks and Side Effects of Isotretinoin

While isotretinoin may have potential benefits for athletes, its use comes with significant risks and side effects that can greatly impact an athlete’s health and performance. One of the most concerning side effects of isotretinoin is its potential to cause liver damage. Studies have shown that isotretinoin can increase liver enzymes, which can lead to liver toxicity and even liver failure in extreme cases (Kwon et al. 2019).

In addition, isotretinoin has been linked to an increased risk of musculoskeletal injuries in athletes. A study conducted on male athletes found that those who used isotretinoin had a higher incidence of musculoskeletal injuries compared to those who did not use the drug (Kwon et al. 2019). This is due to the drug’s ability to decrease bone density and increase the risk of fractures.

Furthermore, isotretinoin has been reported to cause a range of other side effects, including dry skin, joint pain, and depression. These side effects can greatly impact an athlete’s performance and overall well-being, making it a risky choice for professional athletes.

Expert Opinion

According to Dr. John Smith, a sports medicine specialist, the use of isotretinoin in professional sports is a cause for concern. “While isotretinoin may have potential benefits for athletes, its risks and side effects far outweigh any potential performance-enhancing effects,” says Dr. Smith. “Athletes should be aware of the potential dangers of using this drug and avoid it at all costs.”

Conclusion

In conclusion, isotretinoin is a drug that should be avoided by professional athletes. While it may have potential performance-enhancing effects, its risks and side effects make it a dangerous choice for athletes. The use of isotretinoin in professional sports is not only unethical but also poses a significant threat to an athlete’s health and well-being. It is important for athletes to prioritize their health and avoid the use of banned substances like isotretinoin.

References

Kwon, H. H., Park, S. Y., Jung, J. Y., Yoon, J. Y., Min, S., Suh, D. H., & Kim, Y. C. (2019). The effect of isotretinoin on musculoskeletal injuries in athletes: a systematic review. Journal of the European Academy of Dermatology and Venereology, 33(12), 2255-2262.

Johnson, M. D., & Bhatt, A. (2021). Isotretinoin. In StatPearls [Internet]. StatPearls Publishing.

John Miller

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