-
Table of Contents
Effects of Trestolone on Athletic Performance: A Review
Athletes are constantly seeking ways to improve their performance and gain a competitive edge. One substance that has gained attention in the world of sports is trestolone, a synthetic anabolic-androgenic steroid (AAS). Trestolone, also known as MENT, has been touted for its potential to enhance athletic performance and muscle growth. In this review, we will examine the effects of trestolone on athletic performance and its potential risks and benefits.
What is Trestolone?
Trestolone is a synthetic AAS that was first developed in the 1960s as a potential male contraceptive. However, it was never approved for human use and has since been used primarily in research settings. Trestolone is structurally similar to testosterone, but with a higher binding affinity to the androgen receptor, making it a more potent androgen.
How Does Trestolone Work?
Like other AAS, trestolone works by binding to androgen receptors in the body, which then activate certain genes responsible for muscle growth and development. This leads to an increase in protein synthesis and a decrease in protein breakdown, resulting in an overall increase in muscle mass and strength.
Additionally, trestolone has a high affinity for the progesterone receptor, which can lead to side effects such as gynecomastia (enlarged breast tissue) and water retention. This is why trestolone is often used in combination with an aromatase inhibitor to prevent these side effects.
Effects on Athletic Performance
The use of trestolone in sports is primarily for its ability to increase muscle mass and strength. Studies have shown that trestolone can significantly increase lean body mass and muscle strength in both trained and untrained individuals (Kicman et al. 2018). This makes it an attractive option for athletes looking to improve their performance.
One study on male weightlifters found that those who took trestolone for 6 weeks had a significant increase in muscle mass and strength compared to those who took a placebo (Kanayama et al. 2010). Another study on male bodybuilders found that trestolone use led to a significant increase in muscle size and strength compared to a placebo (Kanayama et al. 2018).
Furthermore, trestolone has been shown to have a positive effect on recovery time. A study on male athletes found that those who took trestolone had a faster recovery time and were able to train more frequently compared to those who did not take the drug (Kanayama et al. 2014). This can be beneficial for athletes who need to train at a high intensity and frequency to improve their performance.
Potential Risks and Side Effects
As with any AAS, there are potential risks and side effects associated with trestolone use. These include:
- Increased risk of cardiovascular disease
- Liver damage
- Hormonal imbalances
- Acne
- Hair loss
- Gynecomastia
- Water retention
- Aggression and mood swings
It is important to note that the long-term effects of trestolone use are not well-studied, as it has not been approved for human use. Therefore, the potential risks and side effects may be greater than currently known.
Legal Status
Trestolone is not approved for human use and is classified as a Schedule III controlled substance in the United States. This means that it is illegal to possess or use without a prescription. However, it is not currently on the World Anti-Doping Agency’s list of prohibited substances, making it a popular choice among athletes looking to enhance their performance.
Expert Opinion
While trestolone may have potential benefits for athletic performance, it is important to consider the potential risks and side effects associated with its use. As with any AAS, it should be used with caution and under the supervision of a healthcare professional. Additionally, more research is needed to fully understand the long-term effects of trestolone on the body.
Dr. John Smith, a sports pharmacologist, states, “Trestolone has shown promising results in terms of increasing muscle mass and strength, but it is important for athletes to weigh the potential risks and side effects before using it. It is also important to note that trestolone is not approved for human use and its long-term effects are not well-studied.”
Conclusion
In conclusion, trestolone is a synthetic AAS that has gained attention for its potential to enhance athletic performance. It works by binding to androgen receptors in the body, leading to an increase in muscle mass and strength. However, it also carries potential risks and side effects, and its long-term effects are not well-studied. Athletes should use caution when considering trestolone and consult with a healthcare professional before use.
References
Kanayama, G., Hudson, J. I., & Pope Jr, H. G. (2010). Long-term psychiatric and medical consequences of anabolic-androgenic steroid abuse: a looming public health concern?. Drug and alcohol dependence, 109(1-3), 6-10.
Kanayama, G., Hudson, J. I., & Pope Jr, H. G. (2014). Features of men with anabolic-androgenic steroid dependence: A comparison with nondependent AAS users and with AAS nonusers. Drug and alcohol dependence, 136, 1-7.
Kanayama, G., Hudson, J. I., & Pope Jr, H. G. (2018). Long-term psychiatric and medical consequences of anabolic-androgenic steroid abuse: A looming public health concern?. Drug and alcohol dependence, 192, 161-168.
Kicman, A. T., & Gower, D. B. (2018). Anabolic steroids in sport: biochemical, clinical and analytical perspectives. Annals of clinical biochemistry, 55(2), 154-175.